Abstract: One-to-one laptop initiatives are growing increasingly ubiquitous in the United States and, with a hefty price tag accompanying those initiatives, stakeholders appreciate knowing that they are getting their money's worth when instituting such initiatives. While recent research has demonstrated significant academic gains in one-to-one students, the initiatives have also been promoted as builders of 21st century skills, including communication, collaboration, and IT literacy. However, little has been done to measure or analyze these 21st century skill gains. The aim of this round table is to discuss effective focus group and interview protocols for mixed methods research associated with one-to-one initiatives as they relate to 21st century skills development. A secondary outcome of the round table would be improved understanding of perceptions of students' development of 21st century skills in one-to-one initiatives in public American secondary schools.