Abstract: In recent years, cross-platform mobile applications gaining rapidly popularity with the fast development of HTML5 technology. Web apps and hybrid apps are two major technologies for cross-platform further development in various areas. More and more people are likely spent more time on E-learning with better user experience and responsive applications like native apps and hybrid apps. However, native apps is one multi-platform approach rather than cross-platform solutions. In this paper, we develop the cross-platform hybrid applications for real-time remote experiment based on unified remote experiment framework and unified rendering engine. With the unified framework and unified rendering engine, users can perform the real-time remote experiment at any platforms with hybrid apps.